Despite extensive conventional testing, acute neurological illness in hospitalized patients is difficult to diagnose. In this discussion, Charles Chiu, MD, PhD, discusses a validated UCSF mNGS test that identifies pathogens causing neurological infections in cerebrospinal fluid -- and how a recent multi-hospital study, published in The New England Journal of Medicine, has demonstrated the clinical utility of this test. Dr. Chiu also explains when mNGS testing can be falsely negative and the advantages of considering mNGS as an upfront diagnostic test, rather than a test of last resort.
Read The New England Journal of Medicine paper Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis
Learn more about the UCSF Center for Next-Gen Precision Diagnostics (NGDx).
Professor, Laboratory Medicine
Charles Chiu, M.D./Ph.D. is a Professor of Laboratory Medicine and Medicine, Division of Infectious Diseases at University of California, San Francisco.