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New Discovery Reveals Pathway to Modulate Scarring in Spinal Cord Injury News

New Discovery Reveals Pathway to Modulate Scarring in Spinal Cord Injury

After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it
Forecasting May Help People with Epilepsy Predict Their Seizures News

Forecasting May Help People with Epilepsy Predict Their Seizures

UCSF team discovers brain activity patterns that foreshadow seizures up to 24 hours before they occur.
ER Visit Leads to Moyamoya Disease Diagnosis and Personalized Treatment Plan: UCSF Case Study News

ER Visit Leads to Moyamoya Disease Diagnosis and Personalized Treatment Plan: UCSF Case Study

A 47-year-old woman came to the UCSF emergency department with acute slurred speech along with left-sided facial droop and left-sided numbness, suggesting a stroke. Vessel imaging showed bilateral obstructive arteriopathy, an indication of moyamoya disease.
Life-Changing Care for Untreated Spinal Muscular Atrophy: UCSF Case Study News

Life-Changing Care for Untreated Spinal Muscular Atrophy: UCSF Case Study

An adult man with spinal muscular atrophy (SMA) had been born with limb weakness that progressed to respiratory muscle weakness. Though able to sit independently since childhood, he was never able to walk. Due to the high cost of medication in his home country, he was unable to receive treatment, so he moved to the United States at age 36 to seek therapy for his SMA.
Inpatient Infusion Therapy for Refractory Headaches: UCSF Case Study News

Inpatient Infusion Therapy for Refractory Headaches: UCSF Case Study

The first center of its kind on the West Coast, the UCSF Headache Center provides patients with comprehensive care to relieve the most debilitating headaches. This includes inpatient treatment for people with severe unremitting or recurring headaches for whom first-line therapies have failed.
Improving Measurement of Parkinson’s Disease Severity with AI News

Improving Measurement of Parkinson’s Disease Severity with AI

Despite recent advancements in the treatment of Parkinson’s Disease, it remains a challenge to accurately measure the progression of symptoms in this neurological disorder.
Interdisciplinary Vasculopathy Care Document

Interdisciplinary Vasculopathy Care

The UCSF Vasculopathy Clinic provides comprehensive, interdisciplinary care for patients with moyamoya disease, atherosclerosis and other conditions that cause intracranial vasculopathy.
Signs of Multiple Sclerosis Show Up in Blood Years Before Symptoms News

Signs of Multiple Sclerosis Show Up in Blood Years Before Symptoms

In a discovery that could hasten treatment for patients with multiple sclerosis (MS), UC San Francisco scientists have discovered a harbinger in the blood of some people who later went on to develop the disease. 
New Predictive MS Blood Test May Help Prevent Disability Worsening News

New Predictive MS Blood Test May Help Prevent Disability Worsening

Patients with multiple sclerosis (MS) whose blood tests reveal elevated neurofilament light chain (NfL), a biomarker of nerve damage, are at risk of experiencing disability worsening one to two years later, according to a new study spearheaded by UCSF researchers.
New Alzheimer’s Trial to Combine Anti-Amyloid and Anti-Tau Therapies to Arrest Disease Progression News

New Alzheimer’s Trial to Combine Anti-Amyloid and Anti-Tau Therapies to Arrest Disease Progression

A new study will combine an Alzheimer’s medication that slows disease progression in some patients with two drugs that target disease-driving proteins to see whether their effects can be amplified.
Why Has Progress in the Treatment of Alzheimer’s Disease Taken 30 Years? News

Why Has Progress in the Treatment of Alzheimer’s Disease Taken 30 Years?

UCSF expert examines the past and future of clinical trials for Alzheimer’s Disease.
Telehealth Referral Leads to Diagnosis and Effective Treatment of Rare Neuropathy: Case Study News

Telehealth Referral Leads to Diagnosis and Effective Treatment of Rare Neuropathy: Case Study

A 68-year-old man from Hawaii with acetylcholine receptor (AChR) antibody–positive myasthenia gravis and poorly controlled type 2 diabetes complicated by neuropathy had been receiving intravenous immunoglobulin (IVIg) and taking pyridostigmine for two years when ...
Center for Encephalitis and Meningitis Document

Center for Encephalitis and Meningitis

The UCSF Center for Encephalitis and Meningitis provides comprehensive services to diagnose and treat patients with challenging neuroinflammatory disorders.
UCSF Neurologist Recognized for Innovative Epilepsy Research News

UCSF Neurologist Recognized for Innovative Epilepsy Research

UCSF Neurologist Recognized for Innovative Epilepsy Research American Academy of Neurology to Honor Jon Kleen, MD, PhD with 2023 Dreifuss-Penry Epilepsy Award
Electroconvulsive Therapy for Status Epilepticus and a Genetic Diagnosis for Epilepsy and Renal Failure: UCSF Neurohospitalist Cases News

Electroconvulsive Therapy for Status Epilepticus and a Genetic Diagnosis for Epilepsy and Renal Failure: UCSF Neurohospitalist Cases

One of the first of its kind, the UCSF Neurohospitalist Program specializes in caring for hospitalized patients with complex neurologic disorders.
Minimally Invasive LITT Effective for Recurrent Glioblastoma: A UCSF Case Study News

Minimally Invasive LITT Effective for Recurrent Glioblastoma: A UCSF Case Study

A 65-year-old woman with a small focal recurrence of glioblastoma was treated with laser interstitial thermal therapy (LITT) at UCSF nearly five years after her first tumor resection surgery.
Drug Targeting Tauopathies in Mice Reveals Sex Differences in Response News

Drug Targeting Tauopathies in Mice Reveals Sex Differences in Response

Microglia are cells that are central to both brain health as well as disease progression in many neurological conditions.
Aggressive Surgery Increases Survival with Low-Grade Brain Tumors News

Aggressive Surgery Increases Survival with Low-Grade Brain Tumors

UCSF-Led study shows extensive resection results in longer survival for glioma patients
Cerebral Cavernous Malformation Treatments Relieve Disparate Symptoms News

Cerebral Cavernous Malformation Treatments Relieve Disparate Symptoms

Two patients with severe yet different neurological symptoms were referred to UCSF for emergent neurosurgical evaluation. Both were found to have previously undiagnosed cerebral cavernous malformations (CCMs), but each patient’s treatment was unique.
First “Neuroprosthesis” Expands Vocabulary and Mobility for Man With Paralysis in New Milestone News

First “Neuroprosthesis” Expands Vocabulary and Mobility for Man With Paralysis in New Milestone

The first “neuroprosthesis,” developed by UCSF researchers in 2021, translates brain signals from a man with severe paralysis directly into words that appear as text on a screen. Using this brain-machine interface, he can also move a robotic arm to manipulate objects.
Assessing Cognitive Decline in Primary Care: New Tools and Algorithms for Everyday Practice Video

Assessing Cognitive Decline in Primary Care: New Tools and Algorithms for Everyday Practice

Although timely diagnosis can significantly improve a patient’s future, dementia is underdiagnosed and often detected late.
Genomic Sequencing Is Changing Diagnosis, Treatment for Patients with Brain Cancer News

Genomic Sequencing Is Changing Diagnosis, Treatment for Patients with Brain Cancer

Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy.
DBS Restores Function for Parkinson’s Patient Through New “Sensing” Pacemaker: A UCSF Case Study News

DBS Restores Function for Parkinson’s Patient Through New “Sensing” Pacemaker: A UCSF Case Study

This study allows researchers to continuously record brain physiology from the DBS electrode and automatically adjust the stimulation intensity based on these signals.
Seizures Stopped, Speech Preserved After Rare Auditory Cortex Tumor is Removed: A UCSF Case Study News

Seizures Stopped, Speech Preserved After Rare Auditory Cortex Tumor is Removed: A UCSF Case Study

The extraordinary success was made possible through research on the neural mechanisms of speech by Edward Chang, MD, UCSF neurosurgeon and chair of the Department of Neurological Surgery, and an advanced phase 2 surgical evaluation by the UCSF Epilepsy Center team.

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