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New Method for Rapid, Intraoperative Detection of Residual Tumor Cells Can Vastly Improve Patient Outcomes
It is now possible to detect residual tumor cells during surgery within minutes, a groundbreaking advancement in the surgical treatment of tumors.Cerebral Cavernous Malformation Treatments Relieve Disparate Symptoms
Two patients with severe yet different neurological symptoms were referred to UCSF for emergent neurosurgical evaluation. Both were found to have previously undiagnosed cerebral cavernous malformations (CCMs), but each patient’s treatment was unique.Radioligand Therapy Plus Pembrolizumab May Benefit Patients with Advanced Prostate Cancer
Immune checkpoint inhibitors have demonstrated limited efficacy in treating prostate cancer. Efforts to improve outcomes with combination therapies have mostly failed to demonstrate improvements compared to other types of cancer.Research Reveals Mechanisms at Work in Progression of Pancreatic Cysts to Pancreatic Cancer
Tumor Immune Microenvironments May Provide Clues to Future TherapiesTreating Severe Depression with On-Demand Brain Stimulation
UCSF Health physicians have successfully treated a patient with severe depression by tapping into the specific brain circuit involved in depressive brain patterns and resetting them using the equivalent of a pacemaker for the brain.Autoantibody for Acquired Lipodystrophy Identified, Bringing Hope for Therapeutics
UCSF investigators have found an autoantibody biomarker for acquired lipodystrophy, paving the way for novel treatment options for this complex condition, which causes adipose tissue loss and metabolic complications.UCSF Prostate Cancer Program Awarded SPORE Grant by National Cancer Institute
The UCSF Prostate Cancer Program of the Helen Diller Family Comprehensive Cancer Center is the recipient of the National Cancer Institute’s (NCI) Specialized Programs of Research Excellence (SPORE) grant for prostate cancer.How a Cutting-Edge Genetic Test Helps Ill Newborns, Pregnant Moms
UCSF is first in Northern California to offer rapid test in-house for faster and more accurate diagnosis of rare genetic conditions.Advances in Obesity Medicine: Better Bariatric Surgery Options and Outcomes
With obesity affecting 40% of the U.S. population, bariatric surgeon Jonathan Carter, MD, reviews the devastating health effects of excess body fat and contends that clinicians can no longer sidestep difficult conversations about weight management.Telehealth is as Safe as a Visit to the Clinic for Abortion Pills
Researchers analyzed data from more than 6,000 patients who obtained abortion pills from virtual clinics in 20 states and Washington D.C. between April of 2021 and January of 2022. They found there were no serious adverse events 99.8% of the time, and that abortions did not require follow-up care 98% of the time.Prominent Orthopaedic Surgeon and Researcher to Lead UCSF Orthopaedics Program
C. Benjamin Ma, MD, a highly regarded orthopaedic surgeon and advanced imaging researcher, has been appointed as chair of the UCSF Department of Orthopaedic Surgery. Ma assumed his new role on January 1, 2024.New Research on Optimizing UC Management Through Patient-Centered Tofacitinib Dosing
Tofacitinib is effective for managing ulcerative colitis (UC) and is linked to sustained steroid-free remission. The product label recommends dose de-escalation after eight or 16 weeks, but is this best for patients?Advanced Heart Failure Evaluation and Therapies Program
A full range of therapeutic options – including evidence-based pharmacology, innovative devices and an experienced transplant program – offer personalized approaches to slow progression, prolong survival and improve quality of lifeProstate Cancer Test Is Missing Early Disease in Transgender Women
Transgender women on hormone therapy tend to skew artificially low on prostate cancer screening tests, which may give false reassurance and delay diagnosis and treatment, reports a new study led by UC San Francisco.Paving the Way to Better Outcomes for Rotator Cuff Surgery
Brian T. Feeley, MD, FAOSS, UCSF orthopaedic surgeon and researcher, has been awarded the 2025 Kappa Delta Elizabeth Winston Lanier Award by American Academy of Orthopaedic Surgeons (AAOS).Strategies for Head and Neck Cancer: What to Look, Feel and Listen For
UCSF specialist Chase Heaton, MD, presents a guide to identifying head and neck cancers, including steps, tools and tips for a comprehensive exam; alarm-bell statements from your patients; and the one assumption you want to make about any neck lump.UCSF-Led Study Confirms Some Cancer Immunotherapies May Lead to Myocarditis and Other Potentially Serious Arrhythmias
Immune checkpoint inhibitors (ICIs) have transformed cancer care by unleashing T-cells to fight tumors, but they can cause serious cardiotoxicities including myocarditis.Powerful New Mini Microscopic Will Enable Precision Cancer Surgery
UCSF’s Mekhail Anwar wins an up to $15 million award from ARPA-H to develop a next-generation miniature scanner powerful enough to detect individual cancer cells during surgery.Update on Liver Lesions: What Works in Managing HCC
Based on clear metrics, transplant hepatologist Neil Mehta, MD, presents diagnostic criteria for hepatocellular carcinoma, then shows how UCSF’s HCC team reaches decisions on treatment for individual cases – with plans ranging from resection or ablation to downstaging drugs and transplantation.Melanoma and Skin Cancer Program
Highly specialized care for patients with melanoma, Merkel Cell and other skin cancersNew Evidence on How Alcohol and Caffeine Affect Heart Rhythm Found in UCSF Studies
In separate studies, UC San Francisco researchers examined the effects of two widely consumed beverages – coffee and alcohol – on irregular heartbeat.Making Sense of MGUS: How to Detect Plasma Cell Disorders and Assess Associated Risks
Affecting up to 5% of the U.S. population (and increasingly common with age), monoclonal gammopathy of undetermined significance (MGUS) raises the risk of multiple myeloma, but – as its full name suggests – it can be hard to say by how much.Keys to the Knees: How to Approach a Variety of Meniscus Tears
Historically misunderstood even by sports medicine specialists, meniscus tears are a range of conditions best managed by considering specifics of both the injury and the patient.Burden of Stroke in Women
Vineeta Singh, MD, discusses stroke in women and the relationship between gender and symptoms, risk-factors, prevalence and mortality. Dr. Singh also examines stress and depression as a possible risk factor for stroke in women.