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Update on Brain Metastases: Navigating Treatment Decisions, Reducing Long-Term Harms
In three parts, UCSF neuro-oncology specialists present the latest on managing brain metastases.
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Pediatric Spondylolisthesis: Identifying Surgical Candidates and Selecting the Approach
In a talk with relevance for both adult and pediatric spinal care providers, orthopedic surgeon Sigurd Berven, MD, discusses complex decisions on whether and how to treat a child with high-grade spondylolisthesis.
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Using AI in Electrocardiogram Analysis Can Improve Diagnosis and Treatment of Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden death in adolescents and initial detection is often difficult. A new UCSF study finds that Artificial Intelligence-enhanced (AI)-Electrocardiograms (ECG) may help identify the condition in its earliest stages and monitor important disease-related changes over time.
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Positive Patient Outcomes With Minimally Invasive Skull Base Surgery: UCSF Case Studies
The following case studies describe how Ezequiel (Eze) Goldschmidt, MD, PhD, and the UCSF Brain Tumor Center team used the EEA to successfully remove different types of tumors, including a pituitary adenoma, a craniopharyngioma, an epidermoid cyst and a chondrosarcoma.
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Navigation in Spinal Surgery: An Advantageous Tool of the Trade
Shane Burch, MD. Offering tips from his own experience in both complex and minimally invasive procedures, he explains navigation’s benefits – which include reducing radiation exposure, highlighting individual anatomy and supporting tasks such as screw placement – as well as how to avoid common user errors.
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Deep Brain Stimulation for Medication-Resistant Dystonia: A UCSF Case Study
A 10-year-old boy developed left-foot inversion, which made it difficult for him to walk. He subsequently developed a tremor in his right arm, and then his neck and trunk began to twist. He was seen by several practitioners but did not get a correct diagnosis. At age 17, he was referred to the UCSF Movement Disorders and Neuromodulation Center.
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Current Menopause Care: Understanding and Explaining a Patient’s Options
Gynecologist Mindy Goldman, MD, offers keys to individualizing care in menopause and beyond by looking at factors ranging from family history to having undergone hysterectomy.
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It’s Good to Hear Your Voice: Helping Patients With Vocal Fold Paralysis
Otolaryngologist VyVy N. Young, MD, provides tools for assessing the problem, explains when a workup is needed, and describes treatment options that can make a big difference to patients.
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Lung Cancer Screening: Who, How and When to Refer
†horacic radiologist Brett M. Elicker, MD, and thoracic surgeon Johannes Kratz, MD, present about current lung cancer screening guidelines: who, how, and when to refer.
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Immune Cells Leave Fingerprints on Tumors Metastasized to the Brain Offering Clues to Future Therapies
Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types. Their findings, published the February 17 issue of CELL, provide a potential roadmap for metastatic tumor formation that could be used to design therapies to improve the treatment of metastasized patients.
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Pass the Smell Test: How to Assess Olfactory Loss Linked to COVID and Other Conditions
Otolaryngologist Patricia A. Loftus, MD, discusses what’s known about smell loss in COVID patients as well as its general prevalence in our aging population.
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Pancreatic Cancer Patient Exceeds Life Expectancy After Complex Whipple Procedure at UCSF
A team of UCSF surgeons devised a successful reconstruction approach during a complex Whipple procedure in a 69-year-old man with locally advanced pancreatic adenocarcinoma.
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Breast Cancer Treatment Strategies: Experts Break Down the Latest
Reporting from the renowned San Antonio Breast Cancer Symposium, UCSF specialists present new research findings relevant to the complicated decisions made daily in designing treatment plans for individual patients.
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Will It Pass? Will It Recur? Get Current on Kidney Stone Management
Urologist Justin Ahn, MD, answers crucial questions on preventing and managing kidney stone disease – a condition affecting 10% of the U.S population, with young patients increasingly at risk.
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Treating Severe Depression with On-Demand Brain Stimulation
UCSF Health physicians have successfully treated a patient with severe depression by tapping into the specific brain circuit involved in depressive brain patterns and resetting them using the equivalent of a pacemaker for the brain.
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Benign Prostatic Hyperplasia: Tried-and-True Versus New Treatments
Justin Ahn, MD, covers evaluation essentials for patients with signs of BPH; what to know about various medical therapies, including side effects; and the bounty of today’s surgical options.
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Sorting Cancers by “Immune Archetypes” Represents Potential New Approach to Developing Precision Immunotherapies
Using data from over 300 patient tumors, UCSF researchers have described 12 classes of “immune archetypes” to classify cancer tumors. Their findings, published today in CELL, reveal that cancers from different parts of the body are immunologically similar to one another. These classifications provide unique strategies for enhancing each patient’s choice of cancer immunotherapies.
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Fresh Insight on Cataracts: An Update on Evaluation and Management
Optometrist Emily Eng, OD, MS, FAAO, starts with a refresher on eye anatomy and the factors that make lenses get cloudy, then describes what patients want to know about cataract surgery (the most performed procedure in all of medicine), including pre- and post-op care.
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Gynecologic Cancer and Lynch Syndrome: Identifying Genetic Variants Leads to Precision Treatment
Given the increased risks associated with Lynch syndrome for gynecologic, colon and other cancers, physicians at the UCSF Gynecologic Oncology Center now approach testing, surveillance and treatment based on each patient’s individual genetic risk.
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UCSF Case Study: Same-Day Discharge After Pheochromocytoma Removal
San Francisco endocrine surgeon Sanziana Roman, MD, performed a posterior retroperitoneoscopic adrenalectomy (PRA) to remove a pheochromocytoma. This approach enabled the patient to be discharged home within hours of surgery and avoid prolonged hospitalization, thereby minimizing COVID-19 risk.
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UCSF-led Study Uncovers Unique Stem Cell Trajectory in Lungs Damaged by COVID-19 and Pulmonary Fibrosis
In a collaborative study between UCSF researchers appearing December 30 in Nature Cell Biology, UCSF researchers Jaymin Kathiriya, PhD, and Chaoqun Wang, PhD, discovered that severe lung injuries can trigger lung stem cells to undergo abnormal differentiation. Drs. Kathiriya and Wang, supervised by Hal Chapman, MD, and Tien Peng, MD, respectively, utilized stem cell organoid models to uncover a novel stem cell pathway that is seen in severely injured lungs from COVID-19 and idiopathic pulmonary fibrosis patients.
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How 3D-Printed, Patient-Specific Models Reduce Orthopaedic Surgery Time and Improve Patient Outcomes
In this interview, Alexis Dang, MD, talks about the benefits to patients and surgeons and the first time he used a 3D-printed, patient-specific model for surgical planning.
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UCSF Study Finds 25% of Patients with HPV+ Oropharynx Cancer May Require Chemoradiotherapy After Robotic Surgery
In a nearly 10-year retrospective study involving 136 carefully selected patients with HPV-positive (HPV+) oropharynx cancer, UC San Francisco researchers found that one in four may meet possible indications for adjuvant chemoradiotherapy following transoral robotic surgery (TORS).
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UCSF Osher Center Overview: Integrative Medicine’s Value for Providers and Patients
Sanford C. Newmark, MD, medical director of the UCSF Osher Center for Integrative Medicine, explains what integrative medicine is (hint: it’s neither “alternative medicine” nor homeopathy) and how referred patients can benefit from its proven techniques.
