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New Research on Cell Regeneration Shows Promise for Treating Lung Injury and Fibrosis
In a new study, UCSF researchers showed that they could successfully redirect profibrotic murine lung cells to a nonfibrotic state in which they regenerated alveoli. These findings could lead to novel treatments for lung injury and fibrosis.
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Best Practices for Implementing Virtual and Hybrid Cardiac Rehabilitation Programs
In a new study, UCSF researchers found that patients participating in either virtual or hybrid cardiac rehabilitation (CR) programs showed similar improvements in functional capacity to those of in-person CR program participants. Hybrid programs combine in-person and virtual delivery.
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Virtual Cardiac Rehabilitation Produces Similar Results as In-Person Treatment
UCSF Study Shows Potential Benefit of Expanding Availability for Patients Cardiac rehabilitation (CR) reduces hospitalization and mortality and improves quality of life for patients with cardiovascular disease. Despite its benefits, only 24 percent of eligible patients in the U.S. participate in CR due to financial and logistical barriers.
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Precision Prostate Cancer Treatment Reduces ADT-Related Dementia Risk
In a new study, UCSF researchers found that cumulative androgen deprivation therapy (ADT) exposure was associated with the onset of dementia in a nationwide longitudinal registry of men with prostate cancer.
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Endoscopic Removal of Benign Complex Colorectal Lesions Improves Patient Outcomes
Endoscopic mucosal resection (EMR) is a safe and effective alternative to surgery for benign complex colorectal lesions, according to research led by UCSF gastroenterologist Tonya Kaltenbach, MD.
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Regenerative Medicine Could Soon Transform Treatment of Musculoskeletal Conditions
UCSF’s Brian Feeley, MD, and Xuhui Liu, MD, in collaboration with Kevin Healy, PhD, received a $1.2 million grant for their lab from the California Institute of Regenerative Medicine to continue pursuing their translational research in regenerative medicine.
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Custom Cochlear Implant Programming Shows Promise for Improving Music Perception
A new clinical trial underway at UCSF, High-Resolution CT-Guided Cochlear Implant Programming, aims to improve speech and music perception for cochlear implant (CI) users.
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3D Facial Analysis Shows Biologic Basis for Gender-Affirming Surgery
In order to validate surgical decisions for gender-affirming facial surgery, researchers from the UC San Francisco and the University of Calgary set out to quantify the effect of sex on adult facial size and shape through an analysis of three-dimensional (3D) facial surface images.
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Novel Technique Improves Skin Color Match in Facial Reconstruction
A new procedure developed by UCSF facial plastic surgeons provides patients undergoing microvascular facial reconstruction with a more accurate skin color match than was previously possible.
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New Laryngopharyngeal Sensitivity Test Could Transform Patient Care
UCSF researchers have developed a first-of-its-kind technique to objectively evaluate laryngopharyngeal sensation.
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UCSF Deploys Innovative Data System to Integrate Research and Care
UC San Francisco (UCSF), in collaboration with the Quantum Leap Healthcare Collaborative (QLHC) and the U.S. Food and Drug Administration (FDA) has developed the OneSource system to seamlessly integrate clinical care and research data.
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UCSF’s Dr. Mitchel Berger on the Cancer Moonshot Relaunch
On Feb. 2, 2022, Mitchel Berger, MD, neurosurgeon and director of the UCSF Brain Tumor Center, attended the relaunch of the White House’s Cancer Moonshot initiative at the invitation of President Joe Biden and Dr. Jill Biden.
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UCSF Neurologist to Receive Prestigious Scientific Award
Stephen L. Hauser, MD, Professor of Neurology and Director of the UCSF Weill Institute for Neurosciences, has been chosen by the American Brain Foundation (ABF) to receive its second annual Scientific Breakthrough Award. Hauser is being honored for his career-long commitment to advancing the understanding of the genetic basis, immune mechanisms and treatment of multiple sclerosis (MS).
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Radial Artery Access to Treat a Complex Aneurysm: A UCSF Case Study
UCSF neurosurgeons have extensive experience using the radial artery as an access site for neurointerventional procedures. “Radial artery access results in less blood loss, fewer complications and shorter length of stay, as opposed to femoral access,” said UCSF’s Adib A. Abla, MD, vascular and endovascular neurosurgeon and chief of vascular neurosurgery.
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How to Assign Malignancy Risk to Adnexal Masses Based on Imaging Features
Adoption of the Ovarian-Adnexal Reporting and Data System (O-RADS) by UCSF radiologists, gynecologists and gynecologic oncologists has reduced ambiguity in ultrasound (US) and MRI reporting of ovarian and adnexal lesions, with enormous potential to improve patient outcomes.
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Physician Referral Guide - Focused Ultrasound for Essential Tremor
Essential tremor is the most common movement disorder, affecting an estimated 10 million Americans. Using MR guidance, focused ultrasound can alleviate essential tremor by targeting the ventral intermediate nucleus (Vim) of the thalamus.
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Bladder Cancer Home Test Reduced Need for Cystoscopy During COVID-19
A study led by UCSF urologic cancer surgeons Sima Porten, MD, MPH, and Maxwell Meng, MD, found that use of a home urine test during the COVID-19 pandemic decreased the frequency of surveillance cystoscopy for patients with a history of non-muscle invasive bladder cancer (NMIBC).
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Using AI in Electrocardiogram Analysis Can Improve Diagnosis and Treatment of Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden death in adolescents and initial detection is often difficult. A new UCSF study finds that Artificial Intelligence-enhanced (AI)-Electrocardiograms (ECG) may help identify the condition in its earliest stages and monitor important disease-related changes over time.
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Positive Patient Outcomes With Minimally Invasive Skull Base Surgery: UCSF Case Studies
The following case studies describe how Ezequiel (Eze) Goldschmidt, MD, PhD, and the UCSF Brain Tumor Center team used the EEA to successfully remove different types of tumors, including a pituitary adenoma, a craniopharyngioma, an epidermoid cyst and a chondrosarcoma.
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Deep Brain Stimulation for Medication-Resistant Dystonia: A UCSF Case Study
A 10-year-old boy developed left-foot inversion, which made it difficult for him to walk. He subsequently developed a tremor in his right arm, and then his neck and trunk began to twist. He was seen by several practitioners but did not get a correct diagnosis. At age 17, he was referred to the UCSF Movement Disorders and Neuromodulation Center.
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Immune Cells Leave Fingerprints on Tumors Metastasized to the Brain Offering Clues to Future Therapies
Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types. Their findings, published the February 17 issue of CELL, provide a potential roadmap for metastatic tumor formation that could be used to design therapies to improve the treatment of metastasized patients.
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Pancreatic Cancer Patient Exceeds Life Expectancy After Complex Whipple Procedure at UCSF
A team of UCSF surgeons devised a successful reconstruction approach during a complex Whipple procedure in a 69-year-old man with locally advanced pancreatic adenocarcinoma.
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First Beating Heart Mitral Valve Repair on West Coast Performed at UCSF
The first beating heart mitral valve repair on the West Coast was performed by Tom C. Nguyen, MD, chief of UC San Francisco’s Division of Adult Cardiothoracic Surgery, and his surgical team in September 2021.
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Treating Severe Depression with On-Demand Brain Stimulation
UCSF Health physicians have successfully treated a patient with severe depression by tapping into the specific brain circuit involved in depressive brain patterns and resetting them using the equivalent of a pacemaker for the brain.
