America’s Epidemic of Gun Violence: The State of the Science

For this Grand Rounds, we’ll examine another epidemic plaguing our country: gun violence. Three experts from the front lines of treating victims will look at firearm injury prevention as a topic of medical education, hospital-based violence intervention programs, and how physicians can be leaders and the voices of moral authority about this topic.

Clinical Problem Solving with Sarah Goglin

For Grand Rounds, we have another Clinical Problem Solving (CPS) case to allow listeners to watch in real time how master clinicians reason through challenging cases. While getting the diagnosis “right” is amazing to see, the true learning comes from witnessing how experts navigate the zigs and zags of a diagnostic journey in a case that unfurls in real time (as it does in life, of course).

The Science Behind Real-World Data: Answering Today’s Questions Today

From leveraging EHR data to using real-world evidence for drug discovery, our next Medicine Grand Rounds will delve into how developments in data science are advancing patient care and research. Uma Mahadevan, MD, professor in the Division of Gastroenterology at UCSF Health, will discuss how data applies to research. Marina Sirota, PhD, assistant professor at the Bakar Computational Health Sciences Institute at UCSF, will describe the new era of precision medicine. Erica Farrand, MD, assistant professor in the Division of Pulmonary, Critical Care, Allergy and Sleep Medicine at UCSF Health, will review the UCSF resources available for real-world data analysis. Atul Butte, MD, PhD, director of the Bakar Computational Health Sciences Institute at UCSF and chief data scientist for the entire University of California Health System, will view this topic through a UC-wide lens.

Liver Transplantation: Where Are We Now and Where Are We Going?

Andrew Bindman, professor emeritus at UCSF and executive vice president and chief medical officer for Kaiser Permanente, takes a look at healthcare quality and access, drawing on his vast experiences from serving as a PCP at ZSFG to shaping national health policy during the Obama administration to his current role as CMO of Kaiser. He will share his insights from his personal journey and experiences from ZSFG to the national stage to Kaiser and describe the inner workings of an integrated health plan and medical group.

In Conversation with White House COVID-19 Response Coordinator Ashish Jha

For the past few months, Ashish Jha, former medicine resident and chief resident at UCSF and dean of the School of Public Health at Brown University, has served as the coordinator of the White House COVID-19 response. Ashish returns to Medicine Grand Rounds to share insights from his new role. We’ll review the state of the pandemic, mandates, variants, Paxlovid, vaccines and boosters, funding challenges, and other topical issues. Before and after Ashish's remarks, a panel of UCSF experts (Peter Chin-Hong, Monica Gandhi, and George Rutherford) offer their thoughts and reactions.

Immune Checkpoint Inhibitors: The Good, the Bad, and the Emerging Field of Cardio-Oncology

In this Medicine Grand Rounds we explore the emerging intersection of cardiology and cancer. Javid Moslehi, associate professor in the Division of Cardiology at UCSF Health and our recently recruited chief of cardio-oncology, and Katy Tsai, assistant professor in the Division of Hematology and Oncology at UCSF Health and lead for our newly launched immunotherapy toxicity clinic, will explain how immune checkpoint inhibitors have rapidly transformed oncology care and describe the multi-organ immune-related toxicities associated with checkpoint inhibitors, with a special focus on prevention, diagnosis, and treatment of cardiac toxicity.